First results of clinical study conducted in Lausanne University Hospital demonstrate good correlation between OsCare Sono® measurements and radius BMD

The first results of research conducted in Lausanne University Hospital with the OsCare Sono® were published as a poster at the International Society for Clinical Densitometry 22nd Annual Meeting, on June 1-4 2016 in Galway, Ireland. The study, “Assessment of a New Low Frequency Quantitative Ultrasound (QUS) Device for the Distal Radius”, demonstrated good correlation between the OsCare Sono® measurement results and radial BMD (bone mineral density), as measured by pDXA (peripheral DXA). The finding is in line with previous research findings, which have shown a good correlation to the radial BMD as measured by pQCT (peripheral quantitative computed tomography). The current research with the OsCare Sono® is being conducted in Lausanne University Hospital’s Center of Bone Diseases, Bone and Joint Department, by professor Didier Hans together with radiology technologists S. Soares, R. Pfaffen and A. Casmarrinha-Vieira as well as doctor M. Metzger and chief of department, doctor O. Lamy.

A total of 45 women on average 66 years of age were included in the study. The OsCare Sono® was used to measure the axial speed of low frequency ultrasound (VLF) at the radius. Each woman had three OsCare Sono® measurements in a row with repositioning. The correlation between the OsCare Sono® measurements (average of three measurements) and the radial BMD as measured by pDXA was good, r=0,82. The intra-operator RMS-CV (root mean square coefficient of variation) was 0,33 % for a skilled operator, and 0,41 % between three operators (one skilled and two beginners), indicating good repeatability for the measurement.

According to the researchers, the good correlation with radial bone mineral density may make OsCare Sono® suitable as a potential surrogate for peripheral DXA and for helping to find those individuals who are at a high risk for osteoporosis. Fracture prediction data, which is being collected as part of the research conducted in Lausanne University, will provide important additional information on the OsCare Sono® method.